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In‐Stem Molecular Beacon Containing a Pseudo Base Pair of Threoninol Nucleotides for the Removal of Background Emission
Author(s) -
Kashida Hiromu,
Takatsu Tomohiko,
Fujii Taiga,
Sekiguchi Koji,
Liang Xingguo,
Niwa Kosuke,
Takase Tomokazu,
Yoshida Yasuko,
Asanuma Hiroyuki
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200902367
Subject(s) - perylene , molecular beacon , base (topology) , information retrieval , base pair , computer science , computational biology , chemistry , physics , biology , molecule , biochemistry , mathematics , gene , organic chemistry , mathematical analysis , oligonucleotide
Off means off : An in‐stem molecular beacon in which D ‐threoninol units tether perylene and anthraquinone in the stem region effectively detected target sequences and was able to discriminate a one‐base‐deletion mutant from the wild‐type (full‐match) sequence without background emission (see picture).