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A Simple Electrochemical Cytosensor Array for Dynamic Analysis of Carcinoma Cell Surface Glycans
Author(s) -
Cheng Wei,
Ding Lin,
Ding Shijia,
Yin Yibing,
Ju Huangxian
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200902356
Subject(s) - decipher , glycome , glycan , computer science , glycomics , simple (philosophy) , multiplex , computational biology , information retrieval , biological system , chemistry , biology , bioinformatics , biochemistry , glycoprotein , philosophy , epistemology
Sugar and spice : The title method for the simultaneous multiplex analysis of intact cell‐surface glycans (see picture) shows excellent performance in sensitivity, stability, and practicality. The strategy can be used to analyze the dynamic variation of the cell‐surface glycome and to decipher cellular pathophysiological processes.