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Microfluidic Formation of Monodisperse, Cell‐Sized, and Unilamellar Vesicles
Author(s) -
Ota Sadao,
Yoshizawa Satoko,
Takeuchi Shoji
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200902182
Subject(s) - vesicle , microfluidics , dispersity , bilayer , nanotechnology , lipid bilayer , phospholipid , lipid vesicle , chemistry , biophysics , membrane , materials science , biology , biochemistry , polymer chemistry
Gently down the stream : A microfluidic technique uses a continuous fluid stream to generate monodisperse unilamellar phospholipid vesicles from a single bilayer (see picture). Since the vesicles are robust and efficiently encapsulate high concentrations of various molecules, they are useful as delivery vehicles and as model cellular systems.