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Constructing and Exploiting the Fluorescent Protein Paintbox (Nobel Lecture)
Author(s) -
Tsien Roger Y.
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200901916
Subject(s) - fluorescence , fluorescent protein , computer science , computational biology , green fluorescent protein , biophysics , cognitive science , nanotechnology , chemistry , biology , psychology , physics , biochemistry , materials science , optics , gene
Trip the light fantastic : The green fluorescent protein (GFP) is an invaluable tool for biochemical and medicinal research. It can make tumors, amyloid plaques from Alzheimer′s disease, or pathogenic bacteria equally visible. Ground‐breaking contributions in this field have resulted in the 2008 Nobel Prize for Chemistry being awarded to Osamu Shimomura, Martin Chalfie, and Roger Tsien. The Nobel Laureates describe their research first‐hand.