Ultrasensitive and Selective Colorimetric DNA Detection by Nicking Endonuclease Assisted Nanoparticle Amplification | Zendy

Xu Wei | Zendy; Xue Xuejia | Zendy; Li Tianhu | Zendy; Zeng Huaqiang | Zendy; Liu Xiaogang | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Ultrasensitive and Selective Colorimetric DNA Detection by Nicking Endonuclease Assisted Nanoparticle Amplification

Author(s) -

Xu Wei,

Xue Xuejia,

Li Tianhu,

Zeng Huaqiang,

Liu Xiaogang

Publication year - 2009

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200901772

Subject(s) - endonuclease , oligonucleotide , dna , computational biology , detection limit , microbiology and biotechnology , restriction enzyme , computer science , biology , chemistry , genetics , chromatography

One–two punch : Single stranded DNA sequences can be detected by nicking endonuclease assisted nanoparticle amplification (see picture). The detection system offers a colorimetric detection limit of 0.5 fmol within hours for selected oligonucleotides. Detection of DNA sequences with a single base mismatch or different lengths is also demonstrated.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research