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Highly Water‐Dispersible Biocompatible Magnetite Particles with Low Cytotoxicity Stabilized by Citrate Groups
Author(s) -
Liu Jia,
Sun Zhenkun,
Deng Yonghui,
Zou Ying,
Li Chunyuan,
Guo Xiaohui,
Xiong Liqin,
Gao Yuan,
Li Fuyou,
Zhao Dongyuan
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200901566
Subject(s) - magnetite , biocompatible material , biocompatibility , chemical engineering , chemistry , materials science , nanotechnology , organic chemistry , engineering , metallurgy , biomedical engineering
Uniform magnetite particles stabilized by citrate groups were successfully synthesized by a modified high‐temperature solvothermal reaction. Cell imaging reveals that the water‐dispersible particles can readily penetrate into cells without destroying them, indicating an excellent biocompatibility. A high enrichment capacity of the magnetite particles for separation of trace peptides is observed.