Premium
Indoles from Simple Anilines and Alkynes: Palladium‐Catalyzed CH Activation Using Dioxygen as the Oxidant
Author(s) -
Shi Zhuangzhi,
Zhang Chun,
Li Si,
Pan Delin,
Ding Shengtao,
Cui Yuxin,
Jiao Ning
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200901484
Subject(s) - palladium , catalysis , chemistry , alkyl , catalytic cycle , medicinal chemistry , combinatorial chemistry , organic chemistry
Pd doles it out : A palladium‐catalyzed approach to indoles using the title reaction was achieved (see scheme). The oxidant used in this catalytic cycle was O 2 . Both N‐nonsubstituted and N‐alkyl monosubstituted anilines can be successfully transformed into the corresponding indoles by this method.