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Self‐Mediated Stereoselective Oxidation of Thia‐Capped Cyclodextrins
Author(s) -
Armspach Dominique,
Matt Dominique,
Toupet Loic
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200901200
Subject(s) - stereoselectivity , chemistry , combinatorial chemistry , organic chemistry , catalysis
Self‐control : endo ‐Sulfoxide products can be synthesized selectively by the oxidation of thia‐capped cyclodextrins using m ‐chloroperoxybenzoic acid ( m ‐CPBA) in water. The reaction occurs by the formation of an oxidant–cyclodextrin inclusion complex. Operating in organic media preferentially leads to exo ‐sulfoxide products.