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Using Azobenzene‐Embedded Self‐Assembled Monolayers To Photochemically Control Cell Adhesion Reversibly
Author(s) -
Liu Dingbin,
Xie Yunyan,
Shao Huawu,
Jiang Xingyu
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200901130
Subject(s) - azobenzene , moiety , monolayer , ethylene glycol , adhesion , self assembled monolayer , cell adhesion , hexa , self assembly , chemistry , polymer chemistry , resist , materials science , nanotechnology , stereochemistry , crystallography , molecule , organic chemistry , layer (electronics)
A celling point : A mixed self‐assembled monolayer comprising two types of alkanethiols—one containing an azobenzene unit terminated with a peptide, the other containing a hexa(ethylene glycol) group that resists nonspecific cell adhesion—enables cell adhesion to be modulated photochemically. The reversible conversion of the azobenzene moiety between E and Z configurations allows the surface to either support or resist cell adhesion.