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Lost in Transcription—Inhibition of RNA Polymerase
Author(s) -
Haebich Dieter,
von Nussbaum Franz
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200900338
Subject(s) - rna polymerase , polymerase , transcription (linguistics) , rna polymerase ii , rna dependent rna polymerase , biology , rna , computational biology , dna , genetics , gene , gene expression , promoter , philosophy , linguistics
Form and function : The natural product myxopyronin A provides the key to understanding the inhibition of bacterial RNA polymerase and should spark new ideas for the design of new antibiotics against tuberculosis and other infectious diseases.