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A New Two‐Photon‐Sensitive Block Copolymer Nanocarrier
Author(s) -
Babin Jérôme,
Pelletier Maxime,
Lepage Martin,
Allard JeanFrançois,
Morris Denis,
Zhao Yue
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200900255
Subject(s) - micelle , copolymer , chromophore , nile red , nanocarriers , amphiphile , fluorescence , photochemistry , aqueous solution , absorption (acoustics) , chemistry , materials science , polymer chemistry , organic chemistry , polymer , optics , drug delivery , physics , composite material
Easily disrupted : Micelles of a new amphiphilic block copolymer that bear coumarin groups are sensitive to near infrared light by two‐photon absorption of the chromophore. Disruption of the micelles under irradiation at 794 nm results in release of both photocleaved coumarin and encapsulated nile red from the hydrophobic core of micelle into aqueous solution, which results in opposing changes in fluorescence emission intensity.