Inside Cover: Ribosomal Synthesis of Tricyclic Depsipeptides in Bloom‐Forming Cyanobacteria (Angew. Chem. Int. Ed. 40/2008)

Cage‐like depsipeptides are investigated by C. Hertweck, E. Dittmann, and co‐workers in their Communication on page 7756 ff. The cyanobacterial protease inhibitors microviridin B and J are synthesized from ribosomally produced prepeptides that are transformed into tricyclic depsipeptides. The picture shows a microviridin‐producing cyanobacteria toxic bloom on a lake surface, together with a schematic representation of ribosomal protein biosynthesis and tricyclic depsipeptide cage structures.