Premium
Inside Cover: Real‐Time Detection of Protein–Water Dynamics upon Protein Folding by Terahertz Absorption Spectroscopy (Angew. Chem. Int. Ed. 34/2008)
Author(s) -
Kim Seung Joong,
Born Benjamin,
Havenith Martina,
Gruebele Martin
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200890166
Subject(s) - terahertz radiation , picosecond , folding (dsp implementation) , protein dynamics , absorption (acoustics) , protein folding , cover (algebra) , terahertz spectroscopy and technology , molecular dynamics , spectroscopy , solvent , chemistry , materials science , chemical physics , analytical chemistry (journal) , optoelectronics , optics , physics , computational chemistry , organic chemistry , engineering , mechanical engineering , biochemistry , electrical engineering , quantum mechanics , laser , composite material
Kinetic terahertz absorption (KITA) uses a picosecond‐duration terahertz pulse to monitor directly changes in solvent dynamics during molecular self‐assembly on a reaction time scale of milliseconds to seconds. In their Communication on page 6486 ff., M. Gruebele and co‐workers describe the application of this method to investigate the reorganization of solvent water during the folding of a protein (in this case ubiquitin).