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Selective Adsorption of DNA on Chiral Surfaces: Supercoiled or Relaxed Conformation
Author(s) -
Gan Hui,
Tang Kangjian,
Sun Taolei,
Hirtz Michael,
Li Yong,
Chi Lifeng,
Butz Stefan,
Fuchs Harald
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200806295
Subject(s) - dna supercoil , adsorption , chirality (physics) , molecule , dna , crystallography , chemistry , biophysics , chemical physics , surface (topology) , stereochemistry , materials science , physics , geometry , biology , biochemistry , organic chemistry , dna replication , chiral symmetry breaking , mathematics , quantum mechanics , nambu–jona lasinio model , quark
The right fit : Plasmid DNA molecules show chirality‐dependent interaction with gold surfaces modified by L and D N ‐isobutyrylcysteine. Relaxed DNA molecules have a stronger interaction and adsorption on the L surface, while their counterparts on the D surface maintain a supercoiled conformation, indicating a weak interaction (see picture).