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Fluorescent Color Readout of DNA Hybridization with Thiazole Orange as an Artificial DNA Base
Author(s) -
Berndl Sina,
Wagenknecht HansAchim
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200805981
Subject(s) - fluorescence , dna , orange (colour) , duplex (building) , base pair , chemistry , photochemistry , dimer , biophysics , optics , biology , biochemistry , physics , organic chemistry , food science
A fluorescent chameleon : A single thiazole orange (TO) dye, when used as an artificial DNA base shows the typical green emission, whereas the interstrand TO dimer exhibits an orange excimer‐type emission inside duplex DNA (see picture).