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Coherent Activation of DNA Tweezers: A “SET–RESET” Logic System
Author(s) -
Elbaz Johann,
Moshe Michal,
Willner Itamar
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200805819
Subject(s) - reset (finance) , tweezers , substrate (aquarium) , optical tweezers , chemistry , biophysics , nanotechnology , computer science , physics , materials science , optics , biology , ecology , financial economics , economics
Open sesame : Aptamer–substrate complexes activate the coherent operation of two tweezers that act as a “SET–RESET” logic system. Each tweezer cycles between a fluorescent open state and a closed quenched state (Q=quencher, F=fluorophore) when triggered by adenosine monophosphate (AMP) and adenosine deaminase (AD).