Fluorescence Signal Amplification by Cation Exchange in Ionic Nanocrystals | Zendy

Li Jishan | Zendy; Zhang Tierui | Zendy; Ge Jianping | Zendy; Yin Yadong | Zendy; Zhong Wenwan | Zendy

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Fluorescence Signal Amplification by Cation Exchange in Ionic Nanocrystals

Author(s) -

Li Jishan,

Zhang Tierui,

Ge Jianping,

Yin Yadong,

Zhong Wenwan

Publication year - 2009

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200805710

Subject(s) - fluorescence , divalent , detection limit , nanocrystal , ionic bonding , chemistry , ion exchange , signal (programming language) , ionic liquid , photochemistry , analytical chemistry (journal) , materials science , nanotechnology , ion , optics , chromatography , computer science , physics , catalysis , organic chemistry , programming language

Lighting‐up time : A cation‐exchange reaction releases thousands of divalent cations from nonfluorescent CdSe ionic crystals and triggers fluorescence from thousands of originally nonfluorescent Fluo‐4 fluorophores to obtain a large fluorescence amplification (see picture) and a low detection limit in bioassays. The technique is fast, simple, with a large dye‐to‐reporter labeling ratio, and flexible in selection of nanocrystals and fluorophores.

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