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Synthesis of Unprecedented Scaffold Diversity
Author(s) -
Galloway Warren R. J. D.,
DiázGavilán Mónica,
IsidroLlobet Albert,
Spring David R.
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200805452
Subject(s) - scaffold , diversity (politics) , computer science , sociology , programming language , anthropology
Building a better library : The synthesis of a library of natural‐product‐like small molecules with unprecedented scaffold diversity has been reported (see scheme; Ns=nosylate). The library represents a significant advancement in the capability of synthetic chemists to generate structurally diverse and complex small molecules in a rapid manner.