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Catalytic CF Activation and Hydrodefluorination of Fluoroalkyl Groups
Author(s) -
Meier Gregor,
Braun Thomas
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200805237
Subject(s) - chemistry , catalysis , cationic polymerization , silylation , fluoride , medicinal chemistry , carborane , halogenation , catalytic cycle , polymer chemistry , photochemistry , organic chemistry , inorganic chemistry
A powerful fluoride trap : The extremely Lewis acidic silyl cation [Et 3 Si] + is an active catalyst for the hydrodefluorination of fluoroalkyl groups at room temperature (see example). The carborane anion [CHB 11 H 5 Cl 6 ] − plays an essential role in the catalytic cycle as a weakly coordinating anion that stabilizes cationic intermediates.