High‐Yielding Synthesis of the Anti‐Influenza Neuramidase Inhibitor (−)‐Oseltamivir by Three “One‐Pot” Operations

Taking shortcuts : A remarkably short and high‐yielding asymmetric total synthesis of (−)‐oseltamivir takes advantage of organocatalysis and single‐pot domino operations. The target, known as the drug Tamiflu, is prepared efficiently in a short time, and also its derivatives can be synthesized effectively.