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Silaphenylmercuric Triflate Catalyzed Reactions: Synthesis of a Solid‐Supported Mercuric Salt Catalyst
Author(s) -
Yamamoto Hirofumi,
Sasaki Ikuo,
Hirai Yuki,
Namba Kosuke,
Imagawa Hiroshi,
Nishizawa Mugio
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200804641
Subject(s) - trifluoromethanesulfonate , indole test , catalysis , tandem , salt (chemistry) , chemistry , combinatorial chemistry , continuous flow , organic chemistry , materials science , physics , composite material , mechanics
Let it flow, let it flow : A procedure to generate the first solid‐supported mercuric salt, silaphenylmercuric triflate, is described. Silaphenylmercuric triflate showed remarkable catalytic activity for an indole synthesis, furanoyne cyclization, arylyne cyclization, and tandem carbocyclizations. An efficient flow reaction system for indole synthesis and arylyne cyclization is also described (see figure).