Premium
Telomerization: Advances and Applications of a Versatile Reaction
Author(s) -
Behr Arno,
Becker Marc,
Beckmann Thomas,
Johnen Leif,
Leschinski Julia,
Reyer Sebastian
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200804599
Subject(s) - telomerization , nucleophile , chemistry , organic chemistry , catalysis , raw material , biochemical engineering , combinatorial chemistry , engineering
A chameleonic reaction : The transition‐metal‐catalyzed telomerization of 1,3‐dienes with different nucleophiles leads to the synthesis of numerous products which can be applied in the cosmetic and pharmaceutical industry as well as in polymers and flavors. This Review shows the versatility of the telomerization based on recent research and industrial applications.The transition‐metal catalyzed telomerization of 1,3‐dienes with different nucleophiles leads to the synthesis of numerous products, such as sugar ethers, substituted lactones, or terpene derivatives, which can be applied in the cosmetic and pharmaceutical industry as well as in polymers and flavors. The reaction can be controlled by the choice of the catalytic system, the feedstock, and the reaction conditions. Since telomerization was developed in 1967, there have been many efforts to utilize this reaction. Herein we give an overview of the versatility of telomerization based on examples from research and industry, particular emphasis is placed on catalyst and process development as well as mechanistic aspects.