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Label‐Free Pathogen Detection with Sensor Chips Assembled from Peptide Nanotubes
Author(s) -
de la Rica Roberto,
Mendoza Ernest,
Lechuga Laura M.,
Matsui Hiroshi
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200804299
Subject(s) - nanotechnology , bridging (networking) , peptide , virus , computer science , materials science , computational biology , virology , chemistry , biology , biochemistry , computer network
A robust viral sensor was developed by bridging a pair of gold electrodes with antibody‐coated peptide nanotubes. The nanotubes concentrated the target virus on their surface by molecular recognition between the antibody and the virus (see picture). The nanotubes fit perfectly within the electric field line distribution to enable the extremely sensitive impedimetric detection of viral particles.