An Efficient Approach to Substituted 1,5,7,8,9‐Pentahydrocyclopenta[ h ]‐2‐Benzopyran‐3‐one Derivatives by a Palladium‐Catalyzed Tandem Reaction of 2,7‐Alkadiynylic Carbonates with 2,3‐Allenoic Acids | Zendy

Lian Xiongdong | Zendy; Ma Shengming | Zendy

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An Efficient Approach to Substituted 1,5,7,8,9‐Pentahydrocyclopenta[ h ]‐2‐Benzopyran‐3‐one Derivatives by a Palladium‐Catalyzed Tandem Reaction of 2,7‐Alkadiynylic Carbonates with 2,3‐Allenoic Acids

Author(s) -

Lian Xiongdong,

Ma Shengming

Publication year - 2008

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200803424

Subject(s) - regioselectivity , palladium , intramolecular force , catalysis , benzopyran , chemistry , substrate (aquarium) , tandem , combinatorial chemistry , computer science , stereochemistry , medicinal chemistry , organic chemistry , materials science , biology , ecology , composite material

An unexpected palladium(0)‐catalyzed cyclization of 1 with 2 leads to derivatives 3 or 4 . This reaction allows for broad substrate diversity and proceeds through a proposed sequential process involving regioselective intramolecular carbopalladation.

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