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Chemically Triggered Biodelivery Using Metal–Organic Sol–Gel Synthesis
Author(s) -
Kessler Vadim G.,
Seisenbaeva Gulaim A.,
Unell Maria,
Håkansson Sebastian
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200803307
Subject(s) - biocompatible material , dissolution , colloid , titanium , biomaterial , nanoparticle , chemical engineering , materials science , metal , titanium oxide , oxide , nanotechnology , sol gel , chemistry , organic chemistry , metallurgy , biomedical engineering , medicine , engineering
Living cells can be coated with continuous oxide shells prepared from modified titanium alkoxides (see picture). The shells efficiently isolate the encapsulated biomaterial from the surrounding medium. The resulting colloid media are highly biocompatible; subsequent release (biodelivery) of encapsulated cells or drugs is possible by dissolution of the titania nanoparticles.