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A Trispyrazolylborato Iron Malonato Complex as a Functional Model for the Acetylacetone Dioxygenase
Author(s) -
Siewert Inke,
Limberg Christian
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200802955
Subject(s) - acetylacetone , dioxygenase , chemistry , biochemistry , inorganic chemistry , enzyme
Position available : A pentacoordinate iron(II) complex that binds and activates dioxygen shows dioxygenase activity and cleaves diethyl phenylmalonate, in analogy to acetylacetone dioxygenase (see scheme). The mechanism for the model compound allows interesting hypotheses to be made about the enzyme function.