Photocontrolled Cell Adhesion on a Surface Functionalized with a Caged Arginine‐Glycine‐Aspartate Peptide | Zendy

OhmuroMatsuyama Yuki | Zendy; Tatsu Yoshiro | Zendy

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Photocontrolled Cell Adhesion on a Surface Functionalized with a Caged Arginine‐Glycine‐Aspartate Peptide

Author(s) -

OhmuroMatsuyama Yuki,

Tatsu Yoshiro

Publication year - 2008

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200802731

Subject(s) - peptide , hela , adhesion , glycine , chemistry , cell adhesion , arginine , cell , biochemistry , biophysics , stereochemistry , amino acid , biology , organic chemistry

Sticking to the time and the place : Cell adhesion can be photocontrolled spatiotemporally on a photoresponsive culture dish functionalized with a caged cell‐adhesion motif, namely a nitrobenzyl‐substituted argine‐glycine‐aspartate peptide. Photolysis of the dish cleaves the nitrobenzyl group to produce the active peptide to which HeLa cells can adhere (see micrograph: left half, irradiated).

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