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A Very Simple Copper‐Catalyzed Synthesis of Anilines by Employing Aqueous Ammonia
Author(s) -
Xia Ning,
Taillefer Marc
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200802569
Subject(s) - ammonia , copper , catalysis , aqueous solution , simple (philosophy) , chemistry , ammonia production , combinatorial chemistry , inorganic chemistry , organic chemistry , philosophy , epistemology
Phasing up to matters : The use of aqueous ammonia in a biphasic system with a copper catalyst and diketone supporting ligands allows the catalytic amination of both activated and unactivated aryl and heteroaryl iodides and bromides under very mild conditions (see scheme; R=electron‐donating or ‐withdrawing group; acac=acetylacetonate).
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