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Iron‐Mediated Direct Arylation of Unactivated Arenes
Author(s) -
Wen Jun,
Zhang Ji,
Chen ShanYong,
Li Jing,
Yu XiaoQi
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200802526
Subject(s) - phenylboronic acid , reagent , chemistry , combinatorial chemistry , reaction conditions , coupling reaction , organic chemistry , catalysis
Inexpensive and straightforward : An iron‐mediated cross‐coupling reaction generates biaryl compounds through CH bond activation, using easily handled reagents with low toxicity. Under the optimized reaction conditions a series of substituted phenylboronic acids were coupled with several simple unactivated arenes.