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Vanadium‐Catalyzed Enantioselective Desymmetrization of meso Secondary Allylic Alcohols and Homoallylic Alcohols
Author(s) -
Li Zhi,
Zhang Wei,
Yamamoto Hisashi
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200802523
Subject(s) - desymmetrization , allylic rearrangement , vanadium , enantioselective synthesis , cumene hydroperoxide , catalysis , chemistry , substrate (aquarium) , organic chemistry , oceanography , geology
Desymmetrization isn't complex : The substrate scope for vanadium‐catalyzed epoxidation has been extended. In addition to various allylic alcohols, homoallylic alcohols can also be desymmetrized by using vanadium/bishydroxamic acid complexes (see scheme; CHP=cumene hydroperoxide).