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Cooperative Catalysis of Primary and Tertiary Amines Immobilized on Oxide Surfaces for One‐Pot CC Bond Forming Reactions
Author(s) -
Motokura Ken,
Tada Mizuki,
Iwasawa Yasuhiro
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200802515
Subject(s) - nitromethane , primary (astronomy) , catalysis , oxide , silane , tertiary amine , chemistry , amine gas treating , organic chemistry , combinatorial chemistry , physics , astronomy
D'you know what amine? Primary and tertiary amines are both immobilized on the same silica–alumina surface by silane‐coupling reactions. The resultant silica–alumina‐supported double‐amines are found to exhibit excellent catalysis for 1,3‐dinitroalkane synthesis from various aldehydes with nitromethane. A cooperative catalytic mechanism on the solid surface for this efficient synthesis is proposed.