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Stability and Shape of Hepatitis B Virus Capsids In Vacuo
Author(s) -
Uetrecht Charlotte,
Versluis Cees,
Watts Norman R.,
Wingfield Paul T.,
Steven Alasdair C.,
Heck Albert J. R.
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200802410
Subject(s) - capsid , icosahedral symmetry , characterization (materials science) , chemistry , virology , virus , crystallography , biophysics , materials science , biology , nanotechnology
Viruses at a glance : Ion mobility mass spectrometry allows the identification and differentiation of states in a viral assembly not only by mass but also by conformation. This approach has been used to obtain a biophysical characterization of the hepatitis B virus capsids, and has shown that of its two distinct icosahedral geometries, the spherical capsid structure is preserved in vacuo (see picture).