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Hollow Manganese Oxide Nanoparticles as Multifunctional Agents for Magnetic Resonance Imaging and Drug Delivery
Author(s) -
Shin Jongmin,
Anisur Rahman Md,
Ko Mi Kyeong,
Im Geun Ho,
Lee Jung Hee,
Lee In Su
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200802323
Subject(s) - bifunctional , manganese oxide , nanoparticle , drug delivery , manganese , magnetic resonance imaging , nanotechnology , targeted drug delivery , oxide , materials science , magnetic nanoparticles , medical imaging , iron oxide nanoparticles , drug , chemistry , combinatorial chemistry , organic chemistry , medicine , pharmacology , catalysis , radiology
MRI jack‐o'‐lanterns? Hollow manganese oxide nanoparticles (HMON) show greatly improved relaxivities and drug‐loading capacities compared to those with solid interiors (WMON). Their efficient cellular uptake demonstrates their potential as a bifunctional medical system that combines diagnostic imaging and targeted therapy.