Premium
Synthetic Access to the Chlorocyclopentane Cores of the Proposed Original and Revised Structures of Palau′amine
Author(s) -
Bultman Michael S.,
Ma Jun,
Gin David Y.
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200801969
Subject(s) - sigmatropic reaction , computer science , sequence (biology) , amine gas treating , core (optical fiber) , beckmann rearrangement , information retrieval , combinatorial chemistry , stereochemistry , chemistry , organic chemistry , telecommunications , oxime , biochemistry
Core knowledge : The synthesis of the functionalized cores of both the originally proposed and revised structures of palau′amine have been achieved (see structures). A Diels–Alder/[3,3]‐sigmatropic rearrangement sequence and a Beckmann rearrangement enable the stereocontrolled formation of the highly congested cores.