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Silver‐Catalyzed Transmetalation between Chlorosilanes and Aryl and Alkenyl Grignard Reagents for the Synthesis of Tetraorganosilanes
Author(s) -
Murakami Kei,
Hirano Koji,
Yorimitsu Hideki,
Oshima Koichiro
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200801949
Subject(s) - transmetalation , chemistry , reagent , catalysis , aryl , nucleophile , organic chemistry , silver nitrate , nucleophilic substitution , medicinal chemistry , alkyl
The silver savior : Nucleophilic substitution reactions of chlorosilanes with aryl Grignard reagents have been developed which take place under silver catalysis to afford tetraorganosilanes (see scheme). This transformation is likely to be promoted by diarylargentate reagents that are generated in situ.