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Syntheses, Structures, and Reactivities of Borylcopper and ‐zinc Compounds: 1,4‐Silaboration of an α,β‐Unsaturated Ketone to Form a γ‐Siloxyallylborane
Author(s) -
Kajiwara Takashi,
Terabayashi Tomomi,
Yamashita Makoto,
Nozaki Kyoko
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200801728
Subject(s) - transmetalation , ketone , lithium (medication) , zinc , chemistry , halide , boron , copper , organic chemistry , medicinal chemistry , catalysis , medicine , endocrinology
New borylcopper and borylzinc compounds were synthesized by transmetalation of boryllithium with metal halides. The 1,4‐addition of lithium borylbromocuprate [ B Cu(μ 2 ‐Br)Li(thf) 3 ] to 2‐cyclohexen‐1‐one as a boryl anion, followed by trapping of the resulting boron‐substituted copper enolate with Me 3 SiCl, afforded the γ‐siloxyallylborane.