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An Integrated Self‐Assembled Nanofluidic System for Controlled Biological Chemistries
Author(s) -
Bolinger PierreYves,
Stamou Dimitrios,
Vogel Horst
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200801606
Subject(s) - interfacing , nanoreactor , nanotechnology , computer science , miniaturization , vesicle , service (business) , chemistry , materials science , membrane , nanoparticle , computer hardware , business , biochemistry , marketing
Consecutive enzymatic reactions are executed by mixing attoliter volumes (released from nanometer‐sized lipid vesicles) in a closed femtoliter reactor vessel (a larger unilamellar vesicle), thus controlling the number of reactants with single‐molecule precision. The autonomous nanoreactors need no external interfacing such as outlets or inlets, allowing for extreme miniaturization.