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The Joy and Challenge of Small Rings Metathesis
Author(s) -
Grela Karol
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200801575
Subject(s) - metathesis , olefin metathesis , ring (chemistry) , acyclic diene metathesis , ring closing metathesis , ring opening metathesis polymerisation , enyne metathesis , chemistry , enyne , stereochemistry , polymer , organic chemistry , polymerization , catalysis
Lord of the (Small) Rings : Metathetical opening (ROM/CM) of strained three‐ and four‐membered rings is a well‐established transformation that has been used in numerous total syntheses and in the preparation of polymers. Although small cyclic products generally cannot be easily formed by ring‐closing metathesis (RCM), the recent preparation of substituted cyclobutenes by 1,5‐enyne RCM is a notable example of the formation of a strained four‐membered ring by olefin metathesis.