Antimicrobial Surfaces through Natural Product Hybrids | Zendy

Wach JeanYves | Zendy; Bonazzi Simone | Zendy; Gademann Karl | Zendy

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Antimicrobial Surfaces through Natural Product Hybrids

Author(s) -

Wach JeanYves,

Bonazzi Simone,

Gademann Karl

Publication year - 2008

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200801570

Subject(s) - antimicrobial , natural product , ethylene glycol , product (mathematics) , antibiotics , linker , chemistry , combinatorial chemistry , microbiology and biotechnology , nanotechnology , biology , materials science , computer science , stereochemistry , organic chemistry , mathematics , operating system , geometry

The power of two! A natural product hybrid (see structure) composed of a siderophore and an antibiotic separated by a poly(ethylene glycol) linker enables the preparation of antimicrobial and cell‐resistant surfaces by a simple dip‐and‐rinse procedure. The anachelin siderophore (left) binds strongly to TiO 2 surfaces, and vancomycin is responsible for antibiotic activity.

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