Premium
Synthesis of 2‐Arylbenzoxazoles by Copper‐Catalyzed Intramolecular Oxidative CO Coupling of Benzanilides
Author(s) -
Ueda Satoshi,
Nagasawa Hideko
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200801240
Subject(s) - intramolecular force , regioselectivity , oxidative coupling of methane , copper , catalysis , chemistry , oxidative phosphorylation , combinatorial chemistry , catalytic cycle , molecular oxygen , coupling (piping) , functional group , organic chemistry , materials science , biochemistry , metallurgy , polymer
No need for additives : A wide variety of functionalized 2‐arylbenzoxazoles can be prepared with high functional‐group tolerance and regioselectivity by a copper‐catalyzed intramolecular oxidative CO coupling of benzanilides. The catalytic cycle is completed by the regeneration of the copper catalyst using molecular oxygen as a terminal oxidant without the need for additives.