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Chondramide C: Synthesis, Configurational Assignment, and Structure–Activity Relationship Studies
Author(s) -
Eggert Ulrike,
Diestel Randi,
Sasse Florenz,
Jansen Rolf,
Kunze Brigitte,
Kalesse Markus
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200801156
Subject(s) - scheme (mathematics) , computer science , information retrieval , content (measure theory) , computational biology , mathematics , biology , mathematical analysis
Two solutions for one problem : Of the four isomers of chondramide C synthesized, the two shown in the scheme exhibit nearly the same conformation of the peptide segment and consequently unfold equal biological activities.