Premium
Solution Structures of β Peptides from Raman Optical Activity
Author(s) -
Kapitán Josef,
Zhu Fujiang,
Hecht Lutz,
Gardiner James,
Seebach Dieter,
Barron Laurence D.
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200801111
Subject(s) - raman optical activity , raman spectroscopy , peptide , helicity , chemistry , spectroscopy , circular dichroism , crystallography , materials science , optics , physics , biochemistry , particle physics , quantum mechanics
Chiroptical tool : Good agreement between the experimental and the quantum‐chemically simulated Raman optical activity (ROA) spectrum of a β peptide adopting the ( M )‐3 14 ‐helical conformation (see model peptide; blue N, red O, gray C) demonstrates that ROA spectroscopy has the potential to provide complete structures in solution, including their absolute helicity.