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Copper‐Catalyzed Arylation of Nucleophiles by Using Butadienylphosphines as Ligands: Mechanistic Insight
Author(s) -
Kaddouri Hamid,
Vicente Virginie,
Ouali Armelle,
Ouazzani Fouad,
Taillefer Marc
Publication year - 2009
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200800688
Subject(s) - nucleophile , ligand (biochemistry) , copper , catalysis , combinatorial chemistry , chemistry , scale (ratio) , computer science , organic chemistry , physics , biochemistry , receptor , quantum mechanics
Worth diene for : The butadienylphosphine L (see scheme), obtained on a large scale from a new synthetic method, is an efficient ligand in Ullmann‐type copper‐catalyzed arylation reactions. The use of this phosphorus ligand made it possible to follow the reaction by 31 P NMR spectroscopy and thus to propose a mechanism for the Ullmann reaction.