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Rational Engineering of Dynamic DNA Systems
Author(s) -
Feldkamp Udo,
Niemeyer Christof M.
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200800675
Subject(s) - nanobiotechnology , dna , rational design , nanotechnology , dna nanotechnology , dna computing , chemistry , materials science , biochemistry , nanoparticle
Opening time : A method for the systematic and automatable design of DNA hybridization networks was recently introduced, which was based on the catalytic opening of metastable hairpin loops (see scheme). This technique has various applications in nanobiotechnology, such as the stepwise self‐assembly of DNA scaffolds and the engineering of dynamic DNA devices.