Total Synthesis of Macbecin I | Zendy

Belardi Justin K. | Zendy; Micalizio Glenn C. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Total Synthesis of Macbecin I

Author(s) -

Belardi Justin K.,

Micalizio Glenn C.

Publication year - 2008

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200800400

Subject(s) - benzoquinone , total synthesis , biosynthesis , chemistry , aldehyde , alkyne , alkoxide , computer science , combinatorial chemistry , stereochemistry , biochemistry , enzyme , catalysis

Beyond the bounds of biosynthesis : In a step towards the goal of developing a synthetic pathway for the production of collections of complex molecules related to the benzoquinone ansamycin antibiotics, a natural member of this class was synthesized in a convergent manner through the mild titanium alkoxide mediated coupling of the highly functionalized aniline‐containing alkyne 1 with the sensitive polyunsaturated aldehyde 2 .

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research