Superparamagnetic Nanoparticles as a Powerful Systems Biology Characterization Tool in the Physiological Context | Zendy

Salaklang Jatuporn | Zendy; Steitz Benedikt | Zendy; Finka Andrija | Zendy; O'Neil Conlin P. | Zendy; Moniatte Marc | Zendy; van der Vlies André J. | Zendy; Giorgio Todd D. | Zendy; Hofmann Heinrich | Zendy; Hubbell Jeffrey A. | Zendy; PetriFink Alke | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Superparamagnetic Nanoparticles as a Powerful Systems Biology Characterization Tool in the Physiological Context

Author(s) -

Salaklang Jatuporn,

Steitz Benedikt,

Finka Andrija,

O'Neil Conlin P.,

Moniatte Marc,

van der Vlies André J.,

Giorgio Todd D.,

Hofmann Heinrich,

Hubbell Jeffrey A.,

PetriFink Alke

Publication year - 2008

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200800357

Subject(s) - context (archaeology) , internalization , superparamagnetism , nanoparticle , chemistry , nanotechnology , peptide , characterization (materials science) , isolation (microbiology) , computational biology , biophysics , computer science , biochemistry , biology , materials science , physics , bioinformatics , magnetization , paleontology , quantum mechanics , magnetic field , cell

Spying on SPIONs : Superparamagnetic iron oxide nanoparticles (SPIONs) bearing a mitochondrial targeting peptide (MTP), a cyclic RGD peptide for internalization (cRGD), and a fluorophore for tracking can be targeted to mitochondria. After magnetic isolation from the cells, 48 proteins are identified by mass spectrometry to be interacting with the MTP‐cRGD‐SPIONs in a network that consists of 308 interactions (see picture).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research