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Filamentous Artificial Virus from a Self‐Assembled Discrete Nanoribbon
Author(s) -
Lim Yongbeom,
Lee Eunji,
Yoon YouRim,
Lee Myeong Sup,
Lee Myongsoo
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200800266
Subject(s) - supramolecular chemistry , virus , protein filament , helix (gastropod) , nanotechnology , chemistry , computer science , combinatorial chemistry , computational biology , materials science , biology , crystallography , virology , biochemistry , crystal structure , ecology , snail
Therapeutic viruses : A filament‐shaped artificial virus is formed by using a preorganized supramolecular nanoribbon as a template. The artificial virus (see picture), which is composed of the nanoribbon, small interfering RNAs (blue, double‐helix shape), and hydrophobic guests (red), is highly efficient in delivering genes and drugs to the inside of cells.