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A Highly Efficient and Selective Au I ‐Catalyzed Tandem Synthesis of Diversely Substituted Pyrrolo[1,2‐ a ]quinolines in Aqueous Media
Author(s) -
Liu XinYuan,
Che ChiMing
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200800160
Subject(s) - tandem , aqueous medium , catalysis , combinatorial chemistry , chemistry , aqueous solution , product (mathematics) , simple (philosophy) , scheme (mathematics) , computer science , organic chemistry , materials science , mathematics , composite material , mathematical analysis , geometry , philosophy , epistemology
Bicycles built in water : The Au I ‐catalyzed tandem cyclization of 1‐amino‐4‐alkynes with alkynes in water offers a simple and efficient method for the synthesis of diversely substituted pyrrolo[1,2‐ a ]quinolines with good to excellent product yields and excellent regio‐ and chemoselectivities (see scheme).