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Cover Picture: Rational Design of a Fluorescence‐Turn‐On Sensor Array for Phosphates in Blood Serum (Angew. Chem. Int. Ed. 41/2007)
Author(s) -
Zyryanov Grigory V.,
Palacios Manuel A.,
Anzenbacher Pavel
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200790203
Subject(s) - receptor , fluorescence , hydrogen bond , chemistry , substrate (aquarium) , cover (algebra) , phosphate , biophysics , symmetry (geometry) , biochemistry , physics , optics , biology , molecule , organic chemistry , geometry , mechanical engineering , ecology , engineering , mathematics
The beauty of symmetry is evident in many different forms, such as in The Star of David, rosette windows, and receptor–substrate complexes. P. Anzenbacher, Jr. et al. show in their Communication on page 7849 ff. how C 3 ‐symmetrical receptors with an array of six hydrogen‐bond donors replicate the symmetry in the complex of three phosphate anions within the binding cavity. These receptors were converted into fluorescence sensors capable of detecting phosphates, including AMP and ATP, in water and in blood serum.