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Inside Cover: Bioinspired Design of Nanocages by Self‐Assembling Triskelion Peptide Elements (Angew. Chem. Int. Ed. 12/2007)
Author(s) -
Ghosh Surajit,
Reches Meital,
Gazit Ehud,
Verma Sandeep
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200790041
Subject(s) - nanocages , conjugate , dipeptide , peptide , cover (algebra) , chemistry , molecule , fluorescence , nanotechnology , self assembly , stereochemistry , materials science , physics , biochemistry , organic chemistry , mechanical engineering , mathematical analysis , mathematics , quantum mechanics , engineering , catalysis
Inspired by clathrin , a protein that assembles into closed‐cage structures as a result of the unique triskelion conformation of its three pendant polypeptide chains, E. Gazit, S. Verma, and co‐workers report in their Communication on page 2002 ff. on a synthetic tripodal conjugate with three dipeptide units radiating from a central core. The legs interdigitate to reveal highly spherical structures, as shown in the picture, in which guest molecules such as fluorescent dyes can be trapped and subsequently released.